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The Biochemistry and Function of Linoleic Acid in Human Physiology
Linoleic acid (LA) is a polyunsaturated omega-6 fatty acid essential for human health. It cannot be synthesized by the body and must be obtained through dietary sources such as vegetable oils (e.g., sunflower, safflower, soybean), nuts, seeds, and certain animal products.
What Is Linoleic Acid?
Linoleic acid is an 18-carbon fatty acid with two cis double bonds, classified as an omega-6 fatty acid. It is a vital component of cell membranes and serves as a precursor to bioactive lipids like arachidonic acid, which are involved in inflammatory and immune responses. LA is also crucial for maintaining skin barrier function and overall cellular health.
Health Implications
✅ Potential Benefits
Cardiovascular Health: Higher intake of LA has been associated with improved cardiometabolic outcomes, including lower total and LDL cholesterol levels when compared to saturated fats and carbohydrates
Skin and Hair Health: LA contributes to skin hydration and elasticity. Deficiency can lead to skin disorders such as dryness, acne, and atopic dermatitis